Codeine and promethazine is a combination medication applied to deal with chilly or allergy symptoms for instance runny nose, sneezing, and cough.

Promethazine: Promethazine is really a phenothiazine derivative which differs structurally with the antipsychotic phenothiazines via the presence of a branched aspect chain and no ring substitution.

Promethazine Promethazine competitively antagonize H1 receptors situated in many of the smooth muscle mass such as the gastrointestinal tract, uterus, big blood vessels and bronchial muscle mass.

Drug interactions may perhaps alter how your medications get the job done or increase your chance for significant Unwanted side effects. This doc will not have all possible drug interactions.

Promethazine Promethazine competitively antagonize H one receptors located in almost all of the sleek muscle mass such as the gastrointestinal tract, uterus, large blood vessels and bronchial muscle mass.

No evidence of tumorigenicity was observed in male and female mice at codeine dietary doses around 400 mg/kg/day (approximately such as 44 periods the MRHD on the mg/m two foundation). Codeine was not mutagenic from the in vitro bacterial reverse mutation assay or clastogenic inside the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay. Fertility research with codeine haven't been performed.

Often speak to your healthcare provider to make certain the knowledge displayed on this webpage applies to your own conditions.

Thoroughly evaluate the dose employing a Particular measuring product/spoon. Do not use a family spoon since you might not get the right dose.

Shop at space temperature far from mild and moisture. Do not shop in the bathroom. Tend not to freeze. Keep all medications clear of young children and Animals.

As a result of risk of respiratory melancholy, avoid the use of opioid antitussives, together with Promethazine with Codeine Oral Remedy in clients with compromised respiratory function, sufferers liable to respiratory failure, and in elderly, cachectic, or debilitated sufferers.

Promethazine with Codeine Oral Option really should be utilised with caution in clients with bone-marrow depression. Leukopenia and agranulocytosis happen to be claimed, commonly when promethazine has become used in Affiliation with other regarded marrow-toxic brokers.

Administration of codeine could possibly be accompanied by histamine launch and will be applied with warning in atopic small children.

Recommend people to normally use an exact milliliter measuring machine when measuring and administering Promethazine with Codeine Oral Solution. Inform people that household teaspoon is not an accurate measuring machine and such use could lead on to overdosage and major adverse reactions [see Overdosage ( ten) ]. For prescriptions wherever a measuring system is just not presented, a pharmacist can provide an suitable calibrated measuring device and can offer Recommendations for measuring the correct dose. 5.eight Pursuits Necessitating Mental Alertness: Threats of

It really is made use of To alleviate coughing. It's utilized to relieve allergy indicators. It is read more actually accustomed to ease chilly symptoms. What do I want to tell my medical professional Prior to I get Promethazine and Codeine?